The Rise and Fall of Hydroxychloroquine and Chloroquine in COVID-19Review Published on 2022-12-012023-07-06 Journal: Journal of pharmacy practice [Category] COVID19(2023년), [키워드] Chloroquine coronavirus COVID-19 Hydroxychloroquine. SARS-CoV-2 [DOI] 10.1177/0897190021997399 PMC 바로가기 [Article Type] Review
Review of Hydroxychloroquine Cardiotoxicity: Lessons From the COVID-19 PandemicReview Published on 2022-12-012023-07-10 Journal: Current heart failure reports [Category] COVID19(2023년), [키워드] Cardiomyopathy Cardiotoxicity Chloroquine coronavirus COVID-19 Hydroxychloroquine. [DOI] 10.1007/s11897-022-00581-y PMC 바로가기 [Article Type] Review
Potential interactions between antineoplastic agents and medicines used to treat Covid-19Article Published on 2022-12-012022-11-15 Journal: Journal of Oncology Pharmacy Practice [Category] 치료제, [키워드] accounted Affect antineoplastic agents antineoplastic drug Baricitinib benefit Cancer Chloroquine Combination conducted COVID-19 disease drug drug combinations drug-drug interaction Drug-drug interactions Drug–drug interactions drug–drug interactions. Health Hydroxychloroquine identify Interaction interaction effect interactions involved Lexicomp Medicine Modification outcomes Patient Patients with cancer pharmacokinetic pharmacological intervention plasma concentration Potential professional risk severity therapeutic treat Treatment tyrosine kinase inhibitor was increased [DOI] 10.1177/10781552211040494 PMC 바로가기
Kinetics of Drug Molecule Interactions with a Newly Developed Nano-Gold-Modified Spike Protein Electrochemical Receptor SensorArticle Published on 2022-10-172022-11-15 Journal: Biosensors [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification antiviral drug Chloroquine compounds Concentration correlated COVID-19 Detection sensitivity Developed docking drug drug target drugs electrochemical receptor biosensor exhibit Gln group Hydrogen bond Hydroxychloroquine Interaction investigated kinetic Kinetics limit of detection linear linkage allosterism molecule pandemic Protein provide receptor reported Research residue SARS-CoV-2 sensor Seven spike Spike protein spike protein. the SARS-CoV-2 the spike protein Treatment was used WHO World Health Organization [DOI] 10.3390/bios12100888 PMC 바로가기
Prevalence of ECG testing and characteristics among new hydroxychloroquine and chloroquine users within a multi-center tertiary care centerArticle Published on 2022-10-012022-11-16 Journal: Rheumatology International [Category] COVID19(2023년), SARS, 치료기술, [키워드] affected Arrhythmias baseline cardiac Cardiotoxicity Care Characteristics Chloroquine COVID-19 develop ECG Electrocardiography Electronic health records examined Factor female Follow-up Frequency HCQ Hydroxychloroquine Hydroxychloroquine. initial male management medical system Myocardial infarction Older Patient populations Prospective QTc QTC prolongation raised rheumatic disease subject therapy [DOI] 10.1007/s00296-022-05125-0 PMC 바로가기
Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD)Article Published on 2022-10-012022-11-15 Journal: Natural Product Research [Category] COVID19(2023년), SARS, 치료제, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 antimalarial Antiviral agents Artemisinin bind bio-layer interferometry Chloroquine Complexes Compound computational tool Coronavirus disease-19 Coronavirus-2 COVID-19 demonstrated derivative docking study domain drug candidate host cell in vitro Interaction interfere Invasion investigated mechanism mechanisms metabolite molecular molecular dynamics predicted Protein RBD SARS-CoV-2 SARS-CoV-2 spike protein small molecule Spike protein spike protein. stability treat [DOI] 10.1080/14786419.2021.1925894 PMC 바로가기
Characterization of Entry Pathways, Species-Specific Angiotensin-Converting Enzyme 2 Residues Determining Entry, and Antibody Neutralization Evasion of Omicron BA.1, BA.1.1, BA.2, and BA.3 VariantsArticle Published on 2022-09-142022-11-15 Journal: Journal of Virology [Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] ACE2 ACE2 receptor addition angiotensin-converting enzyme 2 animal ACE2 receptors antibody breakthrough infections Cell characterization Chloroquine D614G D614G variant Determining dose elicit endosomal entry ENhance exhibit greater groups immune evasion Infection inhibitor less Lineage mechanism mRNA vaccination mRNA vaccine neutralization neutralization resistance neutralization titer Neutralizing antibodies neutralizing antibody omicron Pathways pseudovirus public health SARS-CoV-2 SARS-CoV-2 Omicron variants sensitivity spike mutation Spread Substitution substitutions tested TMPRSS2 transmembrane serine protease transmembrane serine protease 2 Transmissibility Transmission vaccination Vaccine vaccine booster variant variants virus entry virus entry pathways. zoonotic [DOI] 10.1128/jvi.01140-22 PMC 바로가기
Does the public know when a scientific controversy is over? Public perceptions of hydroxychloroquine in France between April 2020 and June 2021Article Published on 2022-09-012022-11-15 Journal: Thérapie [Category] SARS, 치료제, [키워드] asked association Chloroquine collected conducted Consensus consequence coronavirus disease Coverage COVID-19 derivative died early stage effective Effectiveness Efficacy Evolution Factor France French Government HCQ Hydroxychloroquine investigated Logistic regression majority media pandemic proportion Public public attitude question respondent Scientific community Sociodemographic Sociology Surveys. therapeutic variable [DOI] 10.1016/j.therap.2022.01.008 PMC 바로가기
Development of spiro-3-indolin-2-one containing compounds of antiproliferative and anti-SARS-CoV-2 properties Research Published on 2022-08-162022-10-05 Journal: Scientific Reports [Category] SARS, 신약개발, 치료제, [키워드] anti-SARS-CoV-2 Apoptosis biological properties cancer cell line Cell cell line Chloroquine Compound Cytometry development Efficacy EGFR explain Flow Hydroxychloroquine inhibitory majority Necrosis standard reference structures Support tested variety Vero Cell viral infection X-ray diffraction [DOI] 10.1038/s41598-022-17883-9 [Article Type] Research
In silico study indicates antimalarials as direct inhibitors of SARS-CoV-2-RNA dependent RNA polymeraseIn silico 연구는 항말라리아제가 SARS-CoV-2-RNA 의존성 RNA 중합효소의 직접적인 억제제임을 나타냅니다.Article Published on 2022-08-012022-09-11 Journal: Journal of biomolecular structure & dynamics [Category] SARS, 치료제, [키워드] active site active sites acute respiratory syndrome coronavirus Amino acid amino acid residue amino acid residues amodiaquine antimalarial Antimalarials Antiviral ATP binding caused Chloroquine co-crystallized Compound conserved coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 crystal structure docked docking results global pandemic Hydroxychloroquine in silico in silico inhibition. indicate inhibitor interactions involved MD simulation molecular pandemic PDB PDB ID performed Poliovirus RdRP RdRps Remdesivir Replication researcher residue residues respiratory RNA RNA dependent RNA polymerase RNA polymerase RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2-RNA dependent RNA polymerase screened Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Simulation study Structure suggested Superimposition Transcription Treatment was used [DOI] 10.1080/07391102.2021.1871956 PMC 바로가기 [Article Type] Article